Statistical and Computational Methods for Genetic Diseases: An Overview

نویسندگان

  • Francesco Camastra
  • Maria Donata Di Taranto
  • Antonino Staiano
چکیده

The identification of causes of genetic diseases has been carried out by several approaches with increasing complexity. Innovation of genetic methodologies leads to the production of large amounts of data that needs the support of statistical and computational methods to be correctly processed. The aim of the paper is to provide an overview of statistical and computational methods paying attention to methods for the sequence analysis and complex diseases.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

An Overview of the New Feature Selection Methods in Finite Mixture of Regression Models

Variable (feature) selection has attracted much attention in contemporary statistical learning and recent scientific research. This is mainly due to the rapid advancement in modern technology that allows scientists to collect data of unprecedented size and complexity. One type of statistical problem in such applications is concerned with modeling an output variable as a function of a sma...

متن کامل

Appraisal of the evolutionary-based methodologies in generation of artificial earthquake time histories

Through the last three decades different seismological and engineering approaches for the generation of artificial earthquakes have been proposed. Selection of an appropriate method for the generation of applicable artificial earthquake accelerograms (AEAs) has been a challenging subject in the time history analysis of the structures in the case of the absence of sufficient recorded accelerogra...

متن کامل

A molecular survey on the genetic variation and mating type of Erysiphe necator Schw. isolates found in Iran, using RAPD technique

Powdery mildew caused by Erysiphe necator, is one of the most economically damaging diseases of grapevine throughout the world. This is the first molecular biology study on this fungus in Iran. The aims of the present study were (a) to analyse genetic diversity between isolates of E. necator fungus in four main grape production regions in Iran, i. e., Qazvin, Alamoot, Takestan and Shahriar and ...

متن کامل

Exposure Assessment to Environmental Pollutants in Human Health Risk Assessment Studies; Overview on New Approaches

Background & objectives: Because of human exposure to various environmental risk factors during the lifetime, the actual exposure estimation has been considered as one of the most important challenges for researchers and decision makers. Considering the contribution of environmental risk factors in the burden of diseases, this study aimed to provide new approaches in exposure assessment filed b...

متن کامل

Heritability for Stroke: Essential for Taking Family History

 There are many well-established factors that influence the risk of stroke including blood pressure, diabetes, low socioeconomic status and smoking, however, the shared genetic resource in members of a family effect on stroke predisposition. Genome-wide association studies (GWAS) have demonstrated evidence of a shared genetic source in stroke risk. This review considered the influence of family...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:

دوره 2015  شماره 

صفحات  -

تاریخ انتشار 2015